Hi Gerard,
Indeed I have published one.... 3WNR. A separate structure 3WNT showing three similar conformations.
Joel
-----Original Message-----
From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of Gerard DVD Kleywegt
Sent: Tuesday, 12 April 2016 6:10 AM
To: [log in to unmask]
Subject: [ccp4bb] Follow-up to a question from 2002
Hi all,
In 2002 I asked the BB a question to which I received many useful responses, showing the power of crowd-sourcing (although that term didn't exist yet at the time I think) - http://www.ysbl.york.ac.uk/ccp4bb/2002/msg00887.html
Now I would like to pick the collective CCP4 Bulletin Brain again:
Does any of you know of any examples (available in the PDB) where the same ligand is observed in two distinctly different conformations (with convincing support in the density) in one and the same structure (i.e., same PDB entry)?
This could for example be two copies of a ligand bound to a dimer in different poses. I'm interested only in distinct sites, not multiple conformations in one site.
I will happily summarise the replies.
Best wishes,
--Gerard
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Gerard J. Kleywegt
http://xray.bmc.uu.se/gerard mailto:[log in to unmask]
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Little known gastromathematical curiosity: let "z" be the
radius and "a" the thickness of a pizza. Then the volume
of that pizza is equal to pi*z*z*a !
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