Dear Filippo,
to perform the kind of study that you want you need to have a database of healthy subjects against which to compare your(s) patient(s).
You either need to acquire a number (at least 20 I'd say) of healthy subjects in your center or to download a number of them from a database (on the top of my head only the ADNI comes to my mind).
The template you linked is good only to perform spatial normalization of the acquired scans.
Cheers,
Luca
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Da: SPM (Statistical Parametric Mapping) <[log in to unmask]> per conto di Filippo A. Antoni <[log in to unmask]>
Inviato: mercoledì 9 marzo 2016 11.31
A: [log in to unmask]
Oggetto: [SPM] HELP: PET Brain analysis
Hi all,
I'm a Nuclear Medicine Student, I'm very new to SPM and none of my colleagues has ever used SPM.
I'm here to ask for help. I've read lot of SPM manual pages but it's still very hard to use.
I'm trying to use SPM to evaluate FDG PET of several patient with dementia/MCI.
The task I'm trying to accomplish is "just" to compare my FDG PET scans with the given template available on SPM site (http://www.fil.ion.ucl.ac.uk/spm/ext/#Dementia_PET) and then get a plot (or a map) of differences between the template and my PET scan.
Can anyone point me to a step-by-step guide or explain how to do this task please?
I've learned how to import/convert DICOM from SPM, realign and coregister but I still can't do analysis.
I've also read some Pubmed articles but I've not found any how-to.
Thanks in advance to anyone can help me.
Filippo
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