A quick literature search shows that CGC has been made and shown to have
Cys-disulfide linkage properties, as well as variant disulfide
isomerases with CXC motifs. (The normal motif is CXXC). See, e.g.
Biochemistry. 2003 May 13; 42(18): 5387; doi:10.1021/bi026993q
Cheers,
_______________________________________
Roger S. Rowlett
Gordon & Dorothy Kline Professor
Department of Chemistry
Colgate University
13 Oak Drive
Hamilton, NY 13346
tel: (315)-228-7245
ofc: (315)-228-7395
fax: (315)-228-7935
email: [log in to unmask]
On 2/19/2016 10:53 AM, Cheng Zhang wrote:
> Hi everyone,
>
> I am wondering if -C-x-C- could form a disulfide bond? x represents
> any amino acid. If not, at least how many residues there should be in
> between two Cys residues in order to allow them form a disulfide bond?
>
> Thanks,
>
> Cheng
>
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