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Posted Sun, 13 Dec 2015 18:11:45
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Project Title: Additional findings from advanced genomic test: exploring understandings and implications
Faculty of Medicine, University of Southampton
This four year PhD studentship leads to a joint PhD with Groningen University, Netherlands and University of Southampton, UK. The research focuses on exploring the ethical, legal and social issues raised by incidental findings –
or findings not related to the clinical question that led to the test – from whole genome analyses. In particular it will analyse the temporal nature of such findings and how the shifting sands of the terminology (e.g. secondary/additional/looked-for/not pertinent etc findings) impact on clinical practice and testees’ understandings regarding the results of advanced genomic tests. Southampton is one of the 11 first wave NHS Genomic Medicine Centres recruiting patients to Genome England’s 100,000 Genomes Project providing a rich source of recruits for empirical ethics and social science research through the clinical ethics and law unit. The ELSi research group in the genetics department at UMCG Groningen performs closely related research with roughly 6000 patients referred annually for genetic/genomic investigations. This PhD will explore some of the communication challenges around the use of novel broad genetic technologies and the range of possible predictive results that arise. For example, how can clinical practice best adapt to the generation of multiple (and sometimes unexpected) predictions from a single test and how might results be recalled and acted upon (eg, surveillance, risk reducing treatments) over the years following a genome test?
There is scope for the candidate to develop the research in areas of specific interest. The researcher’s time will be split between the CELS groups at Southampton (http://www.southampton.ac.uk/cels/index.page) and the ELSI group in Groningen, NL (http://www.rug.nl/research/genetics/research/elsi?lang=en) and the splits can be negotiated according to the successful candidate’s preferences.
Person Specification:
Candidates must be able to undertake research in both Southampton and Groningen. Spoken Dutch is not a prerequisite as Groningen is an international research university. Fluent English speaking and writing skills are essential.
The successful candidate is likely to have a 1st or 2:1 degree in a relevant discipline, and/or second degree with a related Masters. Medical graduates are welcome to apply
Experience of qualitative research methodology is not essential but would be advantageous
Funding information: The award is only eligible to EU applicants. The funding is roughly £20,000 per year for a 4 year period although, depending on professional background, it may be slightly more during the Groningen time. Fees will need to be paid from this during the time in Southampton.
Informal enquiries relating to the project or candidate suitability should be directed to one of the main supervisors:
Professor Anneke Lucassen [log in to unmask]
Professor Irene van Langen [log in to unmask]
Dr Angela Fenwick [log in to unmask]
How to apply:
Please complete the University's online application form, which you can find at
https://studentrecords.soton.ac.uk/BNNRPROD/bzsksrch.P_Login?pos=4361&majr=4361&term=201516#_ga=1.190903020.731406305.1436882451
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