Dear Stephen,
Yeah, I wont' compare the outputs from these two data sets collected with different parameters. I will compare those values within individual. For example, examining time-course changes before and after a certain type of medication within individual, and use their values as an individual index or something like that.
Thank you!
Tae-Ho
Hi
> On 4 Dec 2015, at 19:13, Tae-Ho Lee <[log in to unmask]> wrote:
>
> Dear experts,
>
> Currently I'm working on resting state data collected from two different sites with the same scanner and same length of session (6 min)
> but they were different in terms of repetition time; One is 2s and the other one is 3s.
>
> What I plan to do is as follows.
> 1) Run concatenating group ICA for two dataset together: identify robust RSN components across datasets.
> 2) Run dual regression focusing on stage 1 (estimating individual time course estimation within group-level RSN component) and stage 2 (estimating individual spatial map corresponding to group-level RSN component).
> 3) Do other analysis outside of fsl, melodic and glm with estimated individual time-course and spatial map corresponding to each RSN component at the individual level.
>
> I simply guess based on previous posts regarding this issue (https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind1103&L=fsl&F=&S=&P=31502)
> that it would be okay to the procedure described above without resampling or without separated group-level ICA for each dataset, because I'm not going to do group-level paired comparisons and both dataset are the same in length.
I think it's ok to combine the data to get a joint group-ICA output and then use this to get within-subject node timeseries and spatial maps - but they will not obviously be compatible with each other across the protocols for obvious reasons.
Cheers
> Is my understanding correct? Otherwise, should I run these two dataset separately for concat-group ICA and dual-regression?
> I would appreciate any practical guidelines to handle these different TR situation.
>
> Many thanks!
> Taeho
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Stephen M. Smith, Professor of Biomedical Engineering
Head of Analysis, Oxford University FMRIB Centre
FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK
+44 (0) 1865 222726 (fax 222717)
[log in to unmask] http://www.fmrib.ox.ac.uk/~steve
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