Dear Helmut,
Thank you, I have been reading about the longitudinal toolbox and also applied it to my data. The difference is that I want to calculate the percentage brain (or gray matter) volume change per year for each subject. This is a single value per subject. I guess it can be computed by summing the jacobians within the ICV mask (similar to the "total tissue volume" tool) and normalize that by the follow up time.
However I'm not familiar enough with SPM to be sure what steps to take. My first guess would be to register the average image to dartel and map the ICV mask back?
Thanks for help,
Martijn
> Op 14 dec. 2015 om 16:43 heeft H. Nebl <[log in to unmask]> het volgende geschreven:
>
> Dear Martijn,
>
> The Longitudinal Registration tool as included in SPM12 might be what you are looking for, as it allows tensor-based morphometry. For methodological issues and illustrative applications see Ashburner and Ridgway (2013, http://dx.doi.org/10.3389/fnins.2012.00197 ), for further information see Ziegler et al. (2015, http://dx.doi.org/10.1016/j.neuroimage.2015.06.094 ) / section "Symmetric diffeomorphic registration and image preprocessing".
>
> Best
>
> Helmut
>
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