The molecular biology of life seems inaccessibly complex, and gene
expression is an essential part of it. It is subject to random variation
and not exactly predictable. Mathematical models provide a way to cope
with this: Applied to now available gene expression data of single
cells, they allow to identify underlying gene regulatory processes.
Existing approaches are often oversimplistic. A new project at the
Institute of Computational Biology, Helmholtz Zentrum München,
investigates hybrid models of Markov jump processes and stochastic
differential equations to better model reality.
For this project we are looking for
*1 PhD Student (m/f)*
starting as soon as possible.
Your responsibilities:
- Modelling of gene-regulatory mechanisms using Markov jump processes
and stochastic differential equations; Parameter estimation; Model choice
- Methodological extension of modeling and estimation approaches
- Application to genomic, transcriptomic and proteomic data;
Interpretation of results
- Implementation of algorithms
Your profile:
- Master/Diploma degree in Mathematics, Statistics or related areas
- Very good knowledge of stochastics and statistics; in particular,
essentials of stochastic processes and stochastic differential equations
are advantageous
- Strong programming skills, ideally in R and C++
- Proficiency in written and spoken English
- Being comfortable in interacting with colleagues in an
interdisciplinary setting
Our offer:
- Working in an innovative, well-equipped and scientifically stimulating
surrounding
- Further training opportunities
- Initial short-term employment contract for 3 years with a standard
public service salary (TV EntgO Bund)
Please contact us in case of questions. Application documents
(motivation letter, CV, certificates, two references) should be
submitted as soon as possible and no later than January 24th, 2016, as a
single PDF file via email.
Contact: Dr. Christiane Fuchs, [log in to unmask]
Link to this job post:
http://www.helmholtz-muenchen.de/fileadmin/ICB/Jobs_Teaching/joboffer_ICB_HybridModels.pdf
--
Dr. Christiane Fuchs
Institute of Computational Biology
Tel: +49 89 3187 3385
E-Mail: [log in to unmask]
Home: www.hmgu.de/icb/fuchs
Helmholtz Zentrum Muenchen
Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH)
Ingolstaedter Landstr. 1
85764 Neuherberg
www.helmholtz-muenchen.de
Aufsichtsratsvorsitzende: MinDir'in Baerbel Brumme-Bothe
Geschaeftsfuehrer: Prof. Dr. Guenther Wess, Dr. Nikolaus Blum, Dr. Alfons Enhsen
Registergericht: Amtsgericht Muenchen HRB 6466
USt-IdNr: DE 129521671
You may leave the list at any time by sending the command
SIGNOFF allstat
to [log in to unmask], leaving the subject line blank.
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