Hi Darren
I don't know if you do need to compare like for like sample types so long as you can justify you decision. Unless you plan on running capillary samples in the lab routinely, your best course of action would be to evaluate the results generated on a capillary glucose POCT, vs a lab glucose using what ever procedures you would normally use to generate a lab glucose e.g. fluoride oxalate sample. Most if not all POCT analysers I have encountered fudge the result to get a venous equivalent anyway which should mean results are fairly comparable (at least sample type differences should be accounted for). Even if they do not compare well, knowing how the POCT analysers perform compared to the lab in as close to real world circumstances as possible would give you the most valuable information.
As far as ethics goes, that is trickier. We used to be able to use the old "anonymised sample excess to clinical requirements" but in this case you would need to take additional samples so no easy way around it comes to mind.
Some interesting discussion points - I would love to hear other thoughts.
Rob Moore
Quality Lead
Clinical Biochemistry
Brighton and Sussex University Hospital NHS Trust
________________________________________
From: ACB Point-of-Care Testing [[log in to unmask]] on behalf of Darren Browne [[log in to unmask]]
Sent: 25 September 2015 11:25
To: [log in to unmask]
Subject: Evaluating glucose meters
---
This message was sent from an email address external to NHSmail but gives the appearance of being from an NHSmail (@nhs.net) address. The recipient should verify the sender and content before acting upon information contained within.
The identified sender is [log in to unmask]
---
Hi all,
I wondered if any body can share their experiences of evaluating their POCT glucose meters against the laboratory that will satisfy the ISO 15198 or 22870 standard. I am having difficulty with this as there are issues:
1. Sample type - the evaluation should be done on a like for like basis e.g capillary sample (POCT) vs capillary sample (lab). This is difficult to determine on the lab analyser (small sample size).
2. Sample stability issues - only got a short time to analyse sample particularly if it is a capillary sample.
3. Collecting samples across the measuring range of POCT glucose meters e.g <4 mmol/L
4. Ethical approval
Any thoughts or ideas most welcomed.
Regards,
Darren Browne
Point Of Care Manager
Darent Valley Hospital
Pathology department (Level 3)
Darenth Wood Road, Dartford
Kent DA2 8DA
Tel: 01322 428100 x4876
Email: [log in to unmask]
|