There have been quite a few reports that the addition of a low concentration of alcohol (e.g. isopropanol, a few %) can help to increase the thickness of thin plate crystals like these. However, these are probably in the Hampton additive screen that David Briggs suggested.
Good luck,
Andrew
On 24 Apr 2015, at 04:01, Prerana G. <[log in to unmask]> wrote:
> Dear all,
>
> I am working on a protein (40kDa) which forms very thin plate shaped crystals which diffracts at very low resolution. Protein concentration that i have used for crystallisation is approx. 8mg/ml. I have attached the picture of the protein crystal.
>
>
> How can I improve upon the shape of the crystal?
> <Crystal_1.jpg>
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