Dear colleagues,
I have problems in finding the best design for a learning study comparing old and young participants.
We acquired pre and post resting state connectivity and now want to do a seed-based correlation analysis and compare the pre and post connectivity among the 2 subgroups.
What do you think might be the best design to answer this question?
Especially because there are definite baseline differences between young and old subjects regarding their connectivity. Is there a way to somehow control for these baseline differences to only have the pure learning difference?
I already tried to set up a flexible factorial design and look for interactions but often there are none. If I compute 2sample ttests pre and post, you can see differences between pre and post significant areas but I guess this is not the appropriate way to approach this question.
Any ideas would be highly appreciated.
Thanks a lot in advance.
Elisabeth
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