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MEDICAL: DISEASES: EBOLA :
MEDICAL: TREATMENT :
COUNTRIES: UNITED STATES:
Nina Pham Received Four Experimental Treatments in Effort to Fight Ebola
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Nina Pham Received Four Experimental Treatments in Effort to Fight Ebola
By SEEMA YASMIN
Published: 28 February 2015 10:21 PM
Updated: 28 February 2015 10:46 PM
Dallas News
http://www.dallasnews.com/ebola/headlines/20150228-the-four-
experimental-treatments-that-helped-saved-nurse-nina-pham-from-ebola.ece
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A shorter URL for the above link:
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http://tinyurl.com/o3ydqlu
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Dallas nurse Nina Pham received four experimental Ebola treatments while
battling the deadly disease: plasma from an Ebola survivor, TKM-Ebola,
brincidofovir and ZMapp. Each treatment attacks the virus and supports the
patient in different ways.
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TKM-Ebola
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TKM-Ebola blocks Ebolas ability to make copies of itself. In 2010,
researchers at the University of Texas Medical Branch at Galveston
published a study showing that TKM-Ebola protected monkeys after they had
been infected with a lethal dose of Ebola.
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snip
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Brincidofovir
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Pham received another drug, brincidofovir, that works in a similar way to
TKM-Ebola. It attacks Ebola when it is inside a host cell and stops the
virus from replicating. Its an unusual drug because instead of working
against just one virus, it works against a range of DNA viruses, including
smallpox, adenovirus and cytomegalovirus.
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snip
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ZMapp and plasma
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Pham also received ZMapp, a cocktail of three antibodies that seek out the
Ebola virus in a patients body and neutralize it. ZMapp is difficult to
manufacture, and shortages of the drug hindered the clinical trials needed
to learn about its side effects.
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snip
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Chronic joint pain is listed as another potential side effect of Ebola in
several studies. Extreme fatigue, weakness, headaches and muscle aches can
persist for months after infection in what the World Health Organization
calls post-Ebola syndrome.
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Survivors can suffer socially and psychologically, according to the
International Medical Corps, which talked to small groups of Ebola
survivors in Sierra Leone. They also listed problems with memory and
concentration.
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The complete article may be read at the URL above.
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