Hi all,
I am working on a project in which I am primarily interested in cerebellar activity, but I also want to be able to examine cerebral activity. I want to be able to use smoothing to reduce noise, but I want to make sure what I see in cerebellum is only cerebellar activity, not leakage from inferior occipital regions. I was wondering if it would be valid for me to make a cerebellum-only mask, a cerebrum-only mask, use fslmaths to smooth just inside those masks and zero outside, and then add the outputs--such that overall my data is smoothed but that smoothing has not occurred across the boundary between cerebrum and cerebellum.
I found a link (https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=fsl;4e266bff.1109) to a related topic ("limit smoothing kernel to the mask?") but I wanted to ensure that for my case this type of approach is acceptable.
Can you think of any reasons why this approach would be problematic?
Thanks,
Allison
--
Allison Jack, Ph.D.
Yale Child Study Center
[log in to unmask]
|