Hi Almudena,
You can use Cootilus/Nautilus to rebuild the nucleic acid in your
current density. This is not a direct conversion, but it should be quick
enough.
The conversion form RNA to DNA can be done (outside COOT) in a text
editor by changing the residue names an deleting the O2' atoms. If you
rename uridine (U) to deoxyuridine (DU), you can use 'simple mutate' in
COOT to convert it into thymidine (DT).
The conversion DNA to RNA is more complicated because you need to add
the O2' atoms. Unfortunately, (in my hands) the fill partial residues
function in COOT does not add the missing O2' atoms. You can delete and
re-add the residues, but that is really slow.
HTH,
Robbie
On 01/26/2015 10:01 AM, Almudena Ponce Salvatierra wrote:
> Dear all,
>
> is there a "fast" way of changing the chain type from RNA to DNA or from
> DNA to RNA within coot? I have already quite a bit built into density,
> but it is the wrong kind of nucleic acid.
>
> Best,
>
> Almudena
>
> --
> Almudena Ponce-Salvatierra
> Macromolecular crystallography and Nucleic acid chemistry
> Max Planck Institute for Biophysical Chemistry
> Am Fassberg 11 37077 Göttingen
> Germany
>
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