The Project:
X-ray free-electron lasers (XFELs) are poised to revolutionize
structural biology. They provide highly intense, coherent, femtosecond
X-ray pulses that promise novel approaches to structure determination of
biological objects. We are at the forefront of this development,
designing experimental and computational tools and methods for XFEL
structural biology using appropriate model systems to study biologically
important systems. The applications include imaging of single particles
such as viruses as well as the use of microcrystals for static and
time-resolved studies aimed at understanding biochemical reaction
mechanisms.
We are looking for excellent, highly motivated postdocs and graduate
students.
Your Research Topic:
Will cover one of the on-going projects of the application of FEL's in
structural biology.
Your Tasks:
Participation in FEL (currently LCLS, Stanford, USA and SACLA, Himeji,
Japan) and synchrotron experiments and contribution to practical and/or
computational aspects of:
- Sample preparation and characterization
- Analysis of discrete and continuous diffraction patterns, incl.
algorithm development
- Efficient delivery of biological samples into the X-ray beam
- Structural and mechanistic interpretation
The focus of your project will be determined by your interests and
background; we cover all aspects starting from biochemistry to
theoretical analysis.
Data, injectors and sample systems from previous FEL experiments are
available for an immediate productive start.
The successful candidates:
Will have a Master/diploma or PhD degree in physics, biology, or another
field related to coherent imaging, crystallography, electron microscopy,
image processing or microfluidics/aerosols. You enjoy working in a
multidisciplinary, international group. Good communication skills in
English are a must.
The host laboratory:
We are an interdisciplinary, international team that belongs to the
Dept. of Biomolecular Mechanisms at the MPI for Medical Research in
Heidelberg, which provides a thriving biochemistry/biophysics
environment. We offer a unique environment of top-level scientific
research and state-of-the-art technology. The stimulating and dynamic
environment provides young scientists with an ideal starting-point for
further career steps. Heidelberg is one of the top centers for
biomedical research in Europe, and graduate students have access to
several different Ph.D. programs in Physics or Biology.
Candidates should send their formal application to
[log in to unmask] with the keyword “FEL
application” given in the subject line. Informal inquiries are welcome.
The e-mail should contain a single Portable Document File (PDF) including
- a brief letter, preferably indicating which area of research would be
preferred
- a Curriculum Vitae
- a full list of publications (if applicable)
- a description of past and present research activities (max 1 page) and
- names and addresses of referees (one for Ph.D. / two for postdoctoral
applicants).
The Max Planck Society is an equal opportunity employer and seeks to
increase the percentage of female employees in areas where they are
under-represented. Qualified women are strongly encouraged to apply.
Furthermore, we are also committed to employ more individuals with
disabilities, and therefore actively encourage them to apply.
--
Ilme Schlichting
Max-Planck Institute for Medical Research
Department of Biomolecular Mechanisms
Jahn-Str. 29, D-69120 Heidelberg, Germany
fon : +49 6221 486 500; fax: +49 6221 486 585
e-mail direct: [log in to unmask]
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