Hi Mohamad
The preferred approach is not to include data from different protocols as they can have substantially different properties. Of course that depends on how much different the protocols are, but particularly the b value, the spatial resolution, the SNR and the number of directions can all affect FA.
If you do want to include them, I think that you should at least account in your model for the fact that you have data from different acquisition protocols.
Cheers
Stam
On 18 Oct 2014, at 13:35, M. alshikho <[log in to unmask]> wrote:
> Hi FSL Experts,
> I have DTI data set acquired using different MRIs and different protocols. I want to calculate the Fractional Anisotropy in the right and left hemispheric white matter for all the subjects. My question here how can I include subject with different acquisition parameters in the same analysis. What is the preferred approach in this case and can I run TBSS in such like data set.
>
> Thanks
> Mohamad
|