Hi,
The research group of Dr. Reza Khayat at the City College of New York
(www.khayatlab.org) is seeking candidate postdoctoral fellows to study host
pathogen interaction using a combination of cryo-electron microscopy (cryo-
EM), X-ray crystallography, biophysics and biochemistry. The research group is
particularly interested in elucidating the structural mechanism by which
enveloped and nonenveloped viruses and bacteriophages interact with their
hosts to: acquire cellular entry, hijack cellular machinery, disassemble, replicate,
assemble and egress. The group is also interested in determining the
mechanism by which host antibodies and synthetic DNA aptamers neutralize the
viruses.
The group has dedicated access to a JEOL 2100 and Zeiss EM902 for grid
preparation and screening, and to the resources at the New York Structural
Biology Center (NYSBC) that include facilities for cryo-EM grid and sample
preparation, JEOL 3200FSC, Tecnai F20, JEOL 2100F, JEOL 1230 and a FEI Helios
650. The group also has dedicated access to state-of-art instrumentation to be
housed at the Advanced Science and Research Center (ASRC). Both NYSBC and
ASRC are located in adjacent buildings and within five minute walking distance
from the laboratory (GPS: 40.815927, -73.951201).
The group has open access to multiple Gryphon LCP robots for conducting
crystallization experiments at multiple temperatures, Alchemist DT for screen
optimization, and Minstrel HT for crystal imaging and data storage. The group
shares the following instrumentation: microplate readers, ITC, DLS, CD, and
bioreactors.
Candidates must have a Ph.D., be highly motivated, exhibit independence, and
have experience with protein purification. Salary will be competitive for the NYC
area and be commensurate with experience and prior success. Please send a
cover letter, CV, and the names with contact information for three references to
[log in to unmask]
Best wishes,
Reza
Reza Khayat, PhD
Assistant Professor
The City College of New York
Department of Chemistry, MR-1135
160 Convent Avenue
New York, NY 10031
Tel. (212) 650-6070
www.khayatlab.org
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