Dear All,
As before (see my previous rebuttals on 22/07/2014 and 24/07/2013
of similar "announcements" posted to ALLSTAT on 21/07/2014 and
23/07/2013 respectively), please ignore the "announcement" below
(posted, however, without date or location ... !) of a talk to the
Cambridge Statistics Discussion Group. This talk has already been given
(25 Movember 2013).
The apparent originating source ("Nick Shepley <[log in to unmask]>")
would seem to have nothing to do with the CSDG; there is undoubtedly
some hacking of email accouints behind all this. Indeed, fammix.com
seems to have existed only since 31 August 2013 and is due to expire
on 31 August 2014.
Best wishes to all,
Ted (Chairman of the Cambridge Statistics Discussion Group).
On 08-Aug-2014 08:57:16 Nick Shepley wrote:
> THE CAMBRIDGE STATISTICS DISCUSSION GROUP
>
>
> Department of Applied Mathematics and Theoretical Physics,
> Centre for Mathematical Sciences,
> Wilberforce Road,
> Cambridge, CB3 0WB
>
>
> Design of multi-arm multi-stage trials
>
>
> James Wason
> MRC Biostatistics Unit
>
> Abstract: In many disease areas there are multiple experimental treatments
> awaiting testing in clinical trials. Multi-arm trials provide large gains in
> efficiency over separate randomised trials of each treatment by using a
> shared control group. Further increases in efficiency can be obtained by
> introducing interim analyses at which modifications can be made to the
> proportion of patients allocated to each treatment. Such a design is called a
> multi-arm multi-stage (MAMS) trial. In this talk I will discuss and compare
> three classes of MAMS designs that can be used to increase efficiency and
> ethical properties of a multi-arm trial: group-sequential designs,
> drop-the-loser designs and adaptive randomisation. I will also discuss some
> statistical issues that are common to all three.
>
> Speaker: James Wason is a senior investigator statistician at the MRC
> Biostatistics Unit in Cambridge. As part of the nationwide MRC network of
> Hubs for Trials Methodology Research, he is interested in statistical methods
> for increasing the efficiency of clinical trials.
>
> Directions: The main entrance is reached from Clarkson Road by going along
> the footpath to the right of the Newton Institute, and turning left through
> the gatehouse towards the main building (Pavilion A), which has a glass front
> and a curved grassed roof. The main entrance is in the middle of the glass
> front. Free Parking is available after 5pm on Clarkson and Wilberforce Roads
> and by entering the site off Wilberforce Road. Admittance may be difficult
> after 7:45.
>
>
> Supper: Some members eat regularly in the University Centre before each
> meeting at 6pm. Feel free to join them.
>
> Secretary: Peter Watson, MRC Cognition and Brain Sciences Unit, 15 Chaucer
> Road, Cambridge CB2 7EF;
> telephone 01223 355294 Extension 801; E-mail [log in to unmask]
>
> Slides and .mp3 files of old talks:
> http://www.mrc-cbu.cam.ac.uk/people/peter.watson/csdg.html
>
> You may leave the list at any time by sending the command
>
> SIGNOFF allstat
>
> to [log in to unmask], leaving the subject line blank.
-------------------------------------------------
E-Mail: (Ted Harding) <[log in to unmask]>
Date: 08-Aug-2014 Time: 12:30:29
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