Hi,
I have a protein that is prone to aggregation. I think the problem may be
caused by a stretch of six-residues at the N-terminus that is predicted to form
a beta-strand. I think this beta-strand is open ended and may form beta-
sheets (similar to amyloid fibers) leading to the aggregation I observe. Are
there any chemicals that would disrupt short beta-sheet formation? Thanks.
Best wishes,
Reza
Reza Khayat, PhD
Assistant Professor
The City College of New York
Department of Chemistry, MR-1135
160 Convent Avenue
New York, NY 10031
Tel. (212) 650-6070
www.khayatlab.org
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