Dear FSL experts,
forgive me if the following idea is a mathematical or logical
non-sense, but I would like to hear some expert's opinion on that and
at least know where my thinking went wrong:
Since there is some controversy about slice-timing correction, the way
it is implemented in FEAT, I tried to figure out how can it be
improved without introducing any complicated maths. I thought that
instead of doing the same slice-timing correction on all volumes it
might be more accurate to perform motion-corrected interpolation for
each voxel independently. In the first step, a 4D volume would be
created where relative time-shift (difference between the reference
and actual slice acquisition time) would be stored for each voxel.
Next, MCFLIRT will correct the head motion and resample the functional
series, the same transform and trilinear resampling would be applied
to the time-shift 4D volume. This will create new time-shift values
including the partial volume effect. In the final step, interpolation
would be done between the spatially corresponding voxels using the
weighting information from the time-shift matrix.
I think this way it is possible to interpolate values at the
corresponding brain coordinates and at the same time account for that,
that they actually might be acquired in different slices due to the
head motion.
Thank you for taking your time to consider this idea and/or putting my
erroneous thinking straight.
Cheers
Pavel
--
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-- MUDr. Pavel Hok
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-- Laboratoř funkční magnetické rezonance
-- Neurologická klinika
-- Lékařská fakulta
-- Univerzita Palackého v Olomouci
-- Fakultní nemocnice Olomouc
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-- Laboratory of functional magnetic resonance imaging
-- Department of Neurology
-- Faculty of Medicine and Dentistry
-- Palacky University Olomouc
-- University Hospital Olomouc
-- Czech Republic
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-- I.P. Pavlova 6, 775 20 Olomouc
-- web: fmri.upol.cz
-- tel.: +420 588 443 418
-- e-mail: [log in to unmask]
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