Classical case would be Hexokinase. Also, try the various
states of Fatty Acid Synthase.
Reza Khayat, PhD
Assistant Professor
The City College of New York
Department of Chemistry, MR-1135
160 Convent Avenue
New York, NY 10031
Tel. (212) 650-6070
---- Original message ----
>Date: Thu, 27 Feb 2014 19:43:01 +0000
>From: CCP4 bulletin board <[log in to unmask]> (on behalf
of "Keller, Jacob" <[log in to unmask]>)
>Subject: [ccp4bb] Large Conformational Change Upon Binding
Ligand...
>To: [log in to unmask]
>
>Dear Crystallographers,
>
>Does anyone know of good examples of large, reversible
conformational changes occurring between ligand-free and -
bound states? Could also be a non-relevant molecule binding,
like sulfate or something inducing dubiously -relevant
changes. I already know of the calmodulin and periplasmic
binding protein families, but does anyone know of others out
there?
>
>All the best,
>
>Jacob Keller
>
>*******************************************
>Jacob Pearson Keller, PhD
>Looger Lab/HHMI Janelia Farms Research Campus
>19700 Helix Dr, Ashburn, VA 20147
>email: [log in to unmask]
>*******************************************
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