Dear Patrick,
On Sat, 25 Jan 2014 05:15:53 +0000, Patrick <[log in to unmask]> wrote:
>Hello all,
>
>I know that if you use the non-linear only option for modulated & normalized tissue in the VBM8 toolbox, you do not need to correct for TIV. If one is interested in unmodulated GM density, is it still necessary to correct for TIV in those tissues after normalization?
If you use unmodulated GM density your images are already registered using affine transformation to MNI space and you don't need to additionally correct for TIV. All images are now in normalized space (and no additional affine scaling is included in your modulation step).
Best,
Christian
>
>All the best,
>Patrick
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