Hi SPM users,
I am analyzing data for stroke patient and we have been having issue for two of our patients with abnormal activation maps. There is large amount of activation on the skull and area between skull and gray matter. I have been reading and have been trying to change various parameters in SPM to find a solution for this issue, but havent been successful yet. Hence, i thought of sharing this with SPM users expecting a suggestion which might help me solve this problem.
Also, following pipeline was used to analyze the data
Slice timing
Realign Est & Reslice
Coreg- estimate (ref imge-mean resliced function; source image- T1, other image-masked image)
Segment
Normalise:write (T1 image)
Normalise:write
Smooth
GLM
units of design-secs
Canonical HRF
No derivatives
Classical estimation
Please provide me a thought on where i need to expect changes or source of these abnormal activations
Thanks
Kushal
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