In the case of F1-ATPase they are not biologically independent copies in the a.u. though, rather subunits of a biological complex...
(but perhaps I interpreted the question to narrowly)
Mark J van Raaij
Lab 20B
Dpto de Estructura de Macromoleculas
Centro Nacional de Biotecnologia - CSIC
c/Darwin 3
E-28049 Madrid, Spain
tel. (+34) 91 585 4616
http://www.cnb.csic.es/~mjvanraaij
On 28 Jan 2014, at 05:38, Frank von Delft wrote:
> F1 ATPase. Got some Nobel glamour too.
>
> Sent from tiny silly touch screen
>
> ----- Reply message -----
> From: "Aaron Thompson" <[log in to unmask]>
> Date: Tue, Jan 28, 2014 01:10
> Subject: [ccp4bb] Examples of multiple ASU copies with different conformations
> To: <[log in to unmask]>
>
> The structure of kappa opioid receptor fused with T4 lysozyme (4DJH)
> contains two copies in the ASU – each copy displays a different orientation
> between the receptor and lysozyme.
>
>
> On Mon, Jan 27, 2014 at 10:08 AM, Shane Caldwell <[log in to unmask]
> > wrote:
>
> > Hi ccp4bb,
> >
> > I'm putting together a talk for some peers that highlights strengths and
> > weaknesses of structural models for the outsider. For one point, I'd like
> > to find some examples of proteins that show very different conformations
> > between different copies in the ASU. One example I know of is c-Abl (1OPL),
> > which crystallizes with both autoinhibited and active forms in the ASU,
> > with dramatically different domain organization. I'd like to find some
> > additional examples - can anyone suggest some other structures that have
> > multiple copies with large structural variations?
> >
> > Thanks in advance!
> >
> > Shane Caldwell
> > McGill University
> >
> >
> >
>
>
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