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SPORTS MEDICINE :
MEDICAL: GUIDELINES: CHOLESTEROL :
MEDICAL: PHARMACY PHARMACEUTICAL PHARMACOLOGY: DRUG: STATINS:
Statins Not Linked to Memory Loss, Dementia, Review Suggests
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Statins Not Linked to Memory Loss, Dementia, Review Suggests
Despite FDA warning, researchers found no evidence these drugs cause
declines in thinking ability
November 18, 2013
By Steven Reinberg
Health Day
U.S. News
http://health.usnews.com/health-news/news/articles/2013/11/18/
statins-not-linked-to-memory-loss-dementia-review-suggests
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A shorter URL for the above link:
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http://tinyurl.com/nen3ddb
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MONDAY, Nov. 18 (HealthDay News) -- Cholesterol-lowering statin drugs do
not appear to raise the risk of memory loss or dementia, a new review
finds.
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"In February 2012, largely based on anecdotal reports, the U.S. Food and
Drug Administration issued a safety statement warning patients of possible
adverse mental effects associated with statin use," said senior study
author Dr. Emil deGoma, medical director of the preventive cardiovascular
program at the University of Pennsylvania's Perelman School of Medicine.
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However, the scientific evidence the researchers analyzed showed that
statins -- which include drugs such as Crestor, Lipitor and Zocor --
aren't connected with memory loss or mental declines, deGoma said.
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Some of the studies they reviewed showed that people taking statins
actually reduce their risk for dementia by 13 percent, their risk for
Alzheimer's disease by 21 percent and their risk for other mental problems
by 35 percent, deGoma said.
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"I would not let concerns about adverse effects on mental functioning
influence the decision to start a statin in patients suffering from
cardiovascular disease or [those who are] at risk for cardiovascular
disease," he said.
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In addition, deGoma said, doctors should not assume statins are to blame
when someone taking them becomes forgetful. "We may be doing more harm
than good if we withhold or stop statins -- medications proven to reduce
the risk of heart attack and stroke -- due to fears that statins might
possibly cause memory loss," he said.
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The report was published in the Nov. 19 issue of the journal Annals of
Internal Medicine.
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Dr. Gregg Fonarow, a spokesman for the American Heart Association, said
statins are important in reducing the risk of heart attacks and strokes,
and have been proven safe and effective numerous times.
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"These findings should be highly reassuring to people taking -- or who
should be taking -- statins to reduce their risk of cardiovascular events
and stroke," said Fonarow, a professor of cardiology at the University of
California, Los Angeles.
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"As cardiovascular disease remains the leading cause of death, disability
and health care expenditures, statin therapy, together with a healthy diet
and regular exercise, represents one of the most extensively studied,
safe, effective and value-driven ways to improve individual and
population-level cardiovascular health," he said.
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The complete article may be read at the URL above.
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David Dillard
Temple University
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