Hi Shiva,
There are some other enzyme systems activated by ligand induced oligomerization in addition to the ones on this list:
1) DNA polymerase dimerization on DNA binding
2) Restriction enzyme dimerization on DNA binding (an example is the type IIs FokI)
3) membrane enzyme receptors like receptor tyrosine kinase, etc.
4) metallopeptidases with dimerization domain
Thanks,
Debanu.
-----Original Message-----
From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of Shiva Bhowmik
Sent: Friday, August 09, 2013 10:19 AM
To: [log in to unmask]
Subject: Re: [ccp4bb] Substrate/Ligand Induced Oligomerization of enzymes
Dear All,
Thank you for your responses. Below is the compiled list of examples of substrate/ligand/co-factor induced oligomerization:
http://www.pnas.org/content/97/13/7096.full.pdf
http://www.ncbi.nlm.nih.gov/pubmed/15710608
http://www.ncbi.nlm.nih.gov/pubmed/17725819
http://www.ncbi.nlm.nih.gov/pubmed/14724278
http://www.ncbi.nlm.nih.gov/pubmed/16338409
http://pubs.acs.org/doi/abs/10.1021/bi301067w
http://pubs.acs.org/doi/abs/10.1021/bi2005637
http://pubs.acs.org/doi/abs/10.1021/bi201381e
http://pubs.acs.org/doi/full/10.1021/bi301593c
Have a great weekend. Cheers,
Shiva
On Thu, Aug 8, 2013 at 5:03 PM, Shiva Bhowmik <[log in to unmask]> wrote:
Dear All,
I am looking for references and/or example of substrate or ligand induced oligomerization of enzymes related to activation.
Any help in this regard would be greatly appreciated.
Thanks.
Shiva
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