Dear SPM users
I am a new user of SPM and need some help
I am using the ADNI PET data to compare the difference in glucose metabolism in NC vs AD using two sample t test in SPM.
Group 1 : Normal Control 5 images
Group 2 : AD 5 images
Basic Factorial Models
Design : Two Sample t-testt
Independence : Yes
Variance : Equal
Masking : Relative(Default)
Global Scaling : Mean
Normalization : Proportional Scaling
Contrast as [1 0]
All the images are preprocessed, normalized to MNI Template and smoothed.
I wish to know where I might be going wrong in the analysis part.
Also I need some clarification regarding Cerebellar Normalization. How should I proceed with the same. How should I get the mean cerebellar intensity from the MIP image?
Any help will be greatly appreciated.
Thanks in advance
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