Dear Jiyang,
Yes, with FSL5 you can set up any design using the Glm tool and test it using randomise.
Previously it was difficult to do more complicated tests with FIRST, but now that it works via randomise it is just the same as doing three group comparisons with VBM or FMRI data.
All the best,
Mark
On 29 Jan 2013, at 09:07, Jiyang Jiang <[log in to unmask]> wrote:
> Dear FSLers,
>
> I know it is definitely possible to perform 2-group shape analysis using the well developed FIRST tool box. But I was just wondering if the tool box is able to perform multiple group shape analysis, say three groups (disease, control, and at-risk), to test if differences exist on, for example, hippocampal vertices of subjects of these three groups?
>
> Thanks and regards,
> Jiyang
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