Dear all,
I am currently analyzing a large group of patients compared to controls (total n=170) with VBM. About half the group is made with a T1 TFE SENSE and the other half with a T1 FFE CLEAR, but this is balanced between patients and controls.
I manually reoriented the scans to get proper allignment.
Using DARTEL part of the results seem to be outside the brain, suggesting a problem with normalisation? With the conventional SPM method there is less mismatch, looking more reliable. Do you have any suggestion how I can improve the normalisation to MNI? Is DARTEL able to compare different but comparable T1's?
Many thanks.
Kind regards,
ARE
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