.
.
SPORTS: MEDICINE :
MEDICAL: CONDITIONS: CONCUSSION :
JOURNAL ISSUE:
American Association of Neurological Surgeons.
Journal of Neurosurgery.
December 2012 Issue
.
.
American Association of Neurological Surgeons.
Journal of Neurosurgery.
December 2012 Issue
http://thejns.org/toc/foc/current
.
.
An overview of the basic science of concussion and subconcussion: where we
are and where we are going
Matthew L. Dashnaw, M.D.Pharm.D.1,
Anthony L. Petraglia, M.D.1, and
Julian E. Bailes, M.D.2
1Department of Neurosurgery, University of Rochester Medical Center,
Rochester, New York; and 2Department of Neurosurgery, NorthShore
University Health System, University of Chicago Pritzker School of
Medicine, Evanston, Illinois
Abbreviations used in this paper: BBB = blood-brain barrier; CBF =
cerebral blood flow; TBI = traumatic brain injury.
Address correspondence to: Anthony L. Petraglia, M.D., Department of
Neurosurgery, University of Rochester Medical Center, 601 Elmwood Avenue,
Box 670, Rochester, New York 14642. email:
[log in to unmask]
Please include this information when citing this paper: DOI:
10.3171/2012.10.FOCUS12284.
There has been a growing interest in the diagnosis and management of mild
traumatic brain injury (TBI), or concussion. Repetitive concussion and
subconcussion have been linked to a spectrum of neurological sequelae,
including postconcussion syndrome, chronic traumatic encephalopathy, mild
cognitive impairment, and dementia pugilistica. A more common risk than
chronic traumatic encephalopathy is the season-ending or career-ending
effects of concussion or its mismanagement. To effectively prevent and
treat the sequelae of concussion, it will be important to understand the
basic processes involved. Reviewed in this paper are the forces behind the
primary phase of injury in mild TBI, as well as the immediate and delayed
cellular events responsible for the secondary phase of injury leading to
neuronal dysfunction and possible cell death. Advanced neuroimaging
sequences have recently been developed that have the potential to increase
the sensitivity of standard MRI to detect both structural and functional
abnormalities associated with concussion, and have provided further
insight into the potential underlying pathophysiology. Also discussed are
the potential long-term effects of repetitive mild TBI, particularly
chronic traumatic encephalopathy. Much of the data regarding this syndrome
is limited to postmortem analyses, and at present there is no animal model
of chronic traumatic encephalopathy described in the literature. As this
arena of TBI research continues to evolve, it will be imperative to
appropriately model concussive and even subconcussive injuries in an
attempt to understand, prevent, and treat the associated chronic
neurodegenerative sequelae.
.
Introduction: Concussion: pathophysiology and sequelae
Paul S. Echlin, M.D., M. Sean Grady, M.D., and Shelly D. Timmons, M.D.,
Ph.D
.
Editorial: A prospective study of physician-observed concussion during a
varsity university ice hockey season. Part 1 of 4
Paul S. Echlin, M.D.
.
A prospective study of physician-observed concussion during a varsity
university ice hockey season: incidence and neuropsychological changes.
Part 2 of 4
Paul S. Echlin, M.D., Elaine N. Skopelja, M.A.L.S., Rachel Worsley,
M.P.T., Shiroy B. Dadachanji, M.D., D. Rob Lloyd-Smith, M.D., Jack A.
Taunton, M.Sc., M.D., Lorie A. Forwell, M.Sc.P.T., and Andrew M. Johnson,
Ph.D.
.
A prospective study of physician-observed concussion during a varsity
university hockey season: white matter integrity in ice hockey players.
Part 3 of 4
Inga K. Koerte, M.D., David Kaufmann, M.D., Elisabeth Hartl, M.D., Sylvain
Bouix, Ph.D., Ofer Pasternak, Ph.D., Marek Kubicki, M.D.Ph.D., Alexander
Rauscher, Ph.D., David K. B. Li, M.D., Shiroy B. Dadachanji, M.D., Jack A.
Taunton, M.Sc., M.D., Lorie A. Forwell, M.Sc.P.T., Andrew M. Johnson,
Ph.D., Paul S. Echlin, M.D., and Martha E. Shenton, Ph.D.
.
A prospective study of physician-observed concussion during a varsity
university hockey season: metabolic changes in ice hockey players. Part 4
of 4
Emilie Chamard, B.Sc., Hugo Thret, Ph.D., Elaine N. Skopelja, M.A.L.S.,
Lorie A. Forwell, M.Sc.P.T., Andrew M. Johnson, Ph.D., and Paul S. Echlin,
M.D.
.
An overview of the basic science of concussion and subconcussion: where we
are and where we are going
Matthew L. Dashnaw, M.D.Pharm.D., Anthony L. Petraglia, M.D., and Julian
E. Bailes, M.D.
.
Structural brain injury in sports-related concussion
Scott L. Zuckerman, M.D., Andrew Kuhn, Michael C. Dewan, M.D., Peter J.
Morone, M.D., Jonathan A. Forbes, M.D., Gary S. Solomon, Ph.D., and Allen
K. Sills, M.D.
.
Evaluating the cognitive consequences of mild traumatic brain injury and
concussion by using electrophysiology
Nadia Gosselin, Ph.D., Carolina Bottari, erg., Ph.D., Jen-Kai Chen, Ph.D.,
Sonja Christina Huntgeburth, Louis De Beaumont, Ph.D., Michael Petrides,
Ph.D., Bob Cheung, Ph.D., and Alain Ptito, Ph.D.
.
Long-term functional alterations in sports concussion
Louis De Beaumont, Ph.D., Luke C. Henry, Ph.D., and Nadia Gosselin, Ph.D.
.
Magnetoencephalographic virtual recording: a novel diagnostic tool for
concussion
Matthew Tormenti, M.D., Donald Krieger, Ph.D., Ava M. Puccio, R.N., Ph.D.,
Malcolm R. McNeil, Ph.D., Walter Schneider, Ph.D., and David O. Okonkwo,
M.D., Ph.D.
.
Association between biomechanical parameters and concussion in helmeted
collisions in American football: a review of the literature
Jonathan A. Forbes, M.D., Ahmed J. Awad, M.D., Scott Zuckerman, M.D.,
Kevin Carr, B.S., and Joseph S. Cheng, M.D.
.
Comparative analysis of state-level concussion legislation and review of
current practices in concussion
Krystal L. Tomei, M.D., M.P.H., Christopher Doe, B.S., Charles J.
Prestigiacomo, M.D., and Chirag D. Gandhi, M.D.
.
Letter to the Editor: Cerebral saturation and cerebral blood flow in
head-injured patients
John C. Drummond, M.D., F.R.C.P.C., and Piyush M. Patel, M.D., F.R.C.P.C.
.
Concussion and its association with contact sports
Posted On: November 30, 2012 - 5:30am
Science Codex
http://www.sciencecodex.com/
concussion_and_its_association_with_contact_sports-103010
.
A shorter URL for the above link:
.
http://tinyurl.com/blujt5a
.
.
Charlottesville, VA (November 30, 2012). The JNS Publishing Group is
pleased to announce that the December issue of Neurosurgical Focus is
dedicated to Concussion: Pathophysiology & Sequelae. Guest editors Paul S.
Echlin (Elliott Sports Medicine Clinic, Burlington, ON, Canada), M. Sean
Grady (University of Pennsylvania, Philadelphia, PA), and Shelly D.
Timmons (Geisinger Medical Center/Neurosurgery, Danville, PA) selected 11
articles for this issue that focus on methods of diagnosing concussion and
evaluating its consequences, structural and functional changes that can
occur in the brain following concussion, and changing attitudes and
legislation concerning sports that traditionally carry risks of brain
injury.
.
Concussion, also known as mild traumatic brain injury (TBI), has been
called a "silent epidemic" because the event and its consequences, such as
cognitive and behavioral changes, may be subtle and are not always
recognized.
.
In the first four articles of the December issuea four-part series
offering the results of "a prospective study of physician-observed
concussion during a varsity university hockey season"Dr. Echlin and
colleagues offer new findings of the Hockey Education Concussion Project
(HECP), which focus on concussions sustained by male and female college
hockey players in Canada. In November 2010, these researchers presented
findings from their groundbreaking study of concussion in junior-league
hockey players in Neurosurgical Focus. Today they offer fresh findings on
the incidence of concussion during hockey games, neuropsychological
changes following concussion, and changes in hockey players' white matter
and brain metabolism over the course of the hockey season. The following
universities contributed to the new study: University of Western Ontario,
Harvard University, University of Montreal, University of British
Columbia, and Indiana University. In this study, Echlin and colleagues
added advanced magnetic resonance imaging (MRI) to neuropsychological
tests to follow players' physiological and mental health over an entire
season. They administered the MRI studies and neuropsychological
assessments (ImPACT and SCAT2) to college hockey players at the beginning
of the season, after a diagnosed concussion, and at the end of the season.
In addition, physician and non-physician observers were present at games,
where they could recognize signs and symptoms of concussion on the spot.
.
The incidences of game-related concussions identified by Echlin and
colleagues in the present series, although lower than stated in their 2010
study, were three times higher in male hockey players and five times
higher in female players than those found by other authors. The incidence
in female players was substantially higher than that in male players:
14.93 vs. 7.50 per 1000 athlete exposures during the regular season games.
The authors discuss some findings that led them to believe that
hockey-associated concussion is underreported and other findings that
indicate that the current definition of concussion may need to be
reexamined. The authors also describe their experiences in conducting the
study during hockey games, working with coaches, trainers, and players.
Cultural attitudes about hockey and reticence on the part of team members,
leaders, and others to report concussion events are discussed.
.
snip
.
.
The complete article may be read at the URL above.
.
.
Sincerely,
David Dillard
Temple University
(215) 204 - 4584
[log in to unmask]
http://workface.com/e/daviddillard
Net-Gold
http://groups.yahoo.com/group/net-gold
http://listserv.temple.edu/archives/net-gold.html
Index: http://tinyurl.com/myxb4w
http://groups.google.com/group/net-gold?hl=en
Handouts
http://tinyurl.com/6pvglb4
General Internet & Print Resources
http://guides.temple.edu/general-internet
COUNTRIES
http://guides.temple.edu/general-country-info
EMPLOYMENT
http://guides.temple.edu/EMPLOYMENT
TOURISM
http://guides.temple.edu/tourism
DISABILITIES
http://guides.temple.edu/DISABILITIES
INDOOR GARDENING
http://tech.groups.yahoo.com/group/IndoorGardeningUrban/
Educator-Gold
http://groups.yahoo.com/group/Educator-Gold/
K12ADMINLIFE
http://groups.yahoo.com/group/K12AdminLIFE/
The Russell Conwell Learning Center Research Guide:
THE COLLEGE LEARNING CENTER
http://tinyurl.com/yae7w79
Information Literacy
http://guides.temple.edu/infolit
Nina Dillard's Photographs on Net-Gold
http://tinyurl.com/36qd2o
and also
http://www.flickr.com/photos/neemers/
Twitter: davidpdillard
Bushell, R. & Sheldon, P. (eds),
Wellness and Tourism: Mind, Body, Spirit,
Place, New York: Cognizant Communication Books.
Wellness Tourism: Bibliographic and Webliographic Essay
David P. Dillard
http://tinyurl.com/p63whl
http://tinyurl.com/ou53aw
INDOOR GARDENING
Improve Your Chances for Indoor Gardening Success
http://tech.groups.yahoo.com/group/IndoorGardeningUrban/
http://groups.google.com/group/indoor-gardening-and-urban-gardening
SPORT-MED
https://www.jiscmail.ac.uk/lists/sport-med.html
http://groups.google.com/group/sport-med
http://groups.yahoo.com/group/sports-med/
http://listserv.temple.edu/archives/sport-med.html
HEALTH DIET FITNESS RECREATION SPORTS TOURISM
http://health.groups.yahoo.com/group/healthrecsport/
http://groups.google.com/group/healthrecsport
http://healthrecsport.jiglu.com/
http://listserv.temple.edu/archives/health-recreation-sports-tourism.html
.
.
Please Ignore All Links to JIGLU
in search results for Net-Gold and related lists.
The Net-Gold relationship with JIGLU has
been terminated by JIGLU and these are dead links.
http://groups.yahoo.com/group/Net-Gold/message/30664
http://health.groups.yahoo.com/group/healthrecsport/message/145
Temple University Listserv Alert :
Years 2009 and 2010 Eliminated from Archives
https://sites.google.com/site/templeuniversitylistservalert/
.
.
|
