It may just be noise. Notice there there appears to be no electron density, only difference density.
Mark J van Raaij
Laboratorio M-4
Dpto de Estructura de Macromoleculas
Centro Nacional de Biotecnologia - CSIC
c/Darwin 3
E-28049 Madrid, Spain
tel. (+34) 91 585 4616
http://www.cnb.csic.es/~mjvanraaij
On 5 Nov 2012, at 01:38, yogesh khandokar wrote:
> Dear All
>
> I am working on an enzyme which involved in fatty acid biosynthesis. We solved the crystal structure of it. Biological unit of this enzyme is Hexamer and showing extra electron density in the center of Hexamer. Wincoot software doesn't recognize this extra electron density as water molecules/ substrate.
>
> My question is:Is there any way to find the molecules responsible for extra electron density?
>
> Picture is attached with email.
>
> Thanks in advance for your comments.
>
> Regards
> --
> Yogesh Khandokar
> PhD Student
> School of Biomedical Sciences
> Charles Sturt University
> Wagga Wagga, NSW,
> Australia
> http://www.csu.edu.au/faculty/science/biomed/
>
> <Doc1.doc>
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