I see conflicting advice appearing on the FSL mailing list.
Consider what happens if spatial normalisation is done using a simpler
procedure, such as an affine registration, with one package - but a
more accurate nonlinear procedure in the other package. My best guess
is that an ROI generated via the nonlinear procedure will marginally
better map onto one of the affine aligned brains than will an ROI from
another affine aligned brain. The issue is more to do with alignment
accuracy than use of different packages.
Best regards,
-John
On 28 November 2012 18:13, John Ashburner <[log in to unmask]> wrote:
> Providing all studies have used some representation of MNI space as
> their standard (and not tried to convert their coordinates to T&T
> using one of a number of procedures) then you should be able to
> roughly (very roughly) use regions across different packages.
>
> Best regards,
> -John
>
> On 28 November 2012 17:43, MCLAREN, Donald <[log in to unmask]> wrote:
>> Dear SPM/FSL users,
>>
>> It seems that there are several templates (SPM v FSL) as well as
>> different normalization routines that could result in slight
>> variations of the localization of the results. Do I need to worry
>> about these small differences between methods?
>>
>> In particular, I want to know if I can take regions defined in a study
>> using FLIRT in FSL and use them in my study that has been processed
>> with SPM's non-linear normalization tool. Can I use them as is or is
>> there a transform that can I compute and/or apply to the ROIs to get
>> them into the SPM normalized space.
>>
>> Thank you in advance for your input.
>>
>> Best Regards, Donald McLaren
>> =================
>> D.G. McLaren, Ph.D.
>> Research Fellow, Department of Neurology, Massachusetts General Hospital and
>> Harvard Medical School
>> Postdoctoral Research Fellow, GRECC, Bedford VA
>> Website: http://www.martinos.org/~mclaren
>> Office: (773) 406-2464
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