Hi,
First, thank you for responding.
Second there is some method to my madness. The reason I propose this question is in a recent paper I was arguing that the significant differences I found in TBSS between two groups was in more part due to white matter changes than gray matter changes. To support this claim I performed sienax to get the gray matter volume estimates and used it as a covariate. However, the reviewers thought this was a poor strategy and nitpicked that my changes could be due to regional gray matter changes as opposed to whole brain changes. Therefore, I wanted to use the results from fslvbm as a mask so that I could create a new gray matter volume that only consists of the atrophic regions between the two groups. Hopefully addressing the reviewers point and still bolstering my claim.
Thanks,
Jeremy
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