Dear Experts,
I am relatively new to FMRI analysis and have a very basic question:
We have two groups in an event-related memory design. Our goal is to evaluate the activation for new versus repeated faces between these two groups. Using a main effects analysis, both groups activate frontal and medial temporal lobe areas for new versus repeated faces.
We are interested in the correlative patterns between hippocampal activation and frontal activation for these two groups.
What would be the advantage or disadvantage of just extracting the values for the contrast estimates for both of these areas and analyzing the correlation in let’s say SPSS, versus analyzing the data using PPI? Is it just a matter of looking at total activation versus correlation of time courses?
Many thanks,
Cat
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