Basic Gene Mapping Course
November, 26-30, 2012
Max Delbrück Center (MDC) for Molecular Medicine
Berlin, Germany
The tenth annual gene mapping course will be held at the MDC in Berlin from November 26-30, 2012. The goal of the course is to teach the course participants both theory and application of methods for association studies and linkage analysis (parametric and nonparametric). Additionally the use of exome sequence data to identify rare variants in families will be covered.
Emphasis of this course is on strategies for genetic mapping of human Mendelian and complex traits. It will include theory as well as practical exercises. The exercises will be carried out using a variety of computer programs (LINKAGE, GENEHUNTER, MERLIN, ALLEGRO, SIMWALK2, SLINK, PLINK, TAGGER, etc.). TOPICS include: association studies (case-control & trios); data quality control; tagSNP selection, haplotype reconstruction; controlling for population admixture/substructure; parametric and non-parametric linkage analysis; sample size estimation and power estimation (extended families, sib-pairs and case-control data), using exome sequence data in families to identify rare variants, controlling the family wise error rate (FWER) and estimating empirical p-values. The organizers and instructors for the course are Suzanne Leal (Baylor College of Medicine) and Michael Nothnagel ( University of Cologne & Max Delbrück Center). The maximum number of participants is 30.
For additional information on the course, course schedule and application form please visit the course website: http://linkage.rockefeller.edu/suzanne/Berlin_Basic_Gene_Mapping_Course_2012.htm
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