Dear Stephen Smith,
Thank you very much for your response.
>We don't generally recommend using a lowpass filter, although if you are concerned about high-frequency artefacts that have not been cleaned out of your data >through other steps it could help robustify things.
Could this lowpass filter affect the next procedures? I do this question because when I perform DR I need about 1 day (#23 patients), I know that my PC is not the best but the time that is normally needed is so much?
>Not sure what you mean by "activated" - was this not resting data?
Sorry my expression was not so precise. I meant that I have performed the concat MELODIC on controls and patients separately. The DMN component from each group seems to be different. In particular, the number of voxels in PCC and MTFL is different between these two groups. So, someone could expect that after DR there must be significant differences in these regions. Although, when I perform the DR I cannot find any difference in the great majority of the components. As mentioned in the previous message, there are only some differences (only a few pixels) in the Dorsal Visual stream and a small area in DMN that is in different position from PCC and MTFL. I hope that now is more clear. In addition, it is known from the literature that patients with PCA face visual difficulties so it is a bit strange that I cannot find significant differences in other RSNs involved in the vision. In order to find statistical significant differences I use the #compoment_tfce_corrp_#contrast map... is that correct?
Thank you for your time,
Ioannis
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