Hello FSL users and experts,
I want to do a group comparison of resting-state fMRI data, my concert is that the control subjects (n=25) were scanned in our research center using a 3 Tesla Siemens Trio scanner . While the patients subjects (n=25) were scanned in a different center using an identical scanner 3 Tesla Siemens Trio scanner.
Questions:
1) So, is it possible to do the group comparison?
2) If so, Even both scanners are 3 Tesla Siemens Trio scanner, Do I need to model in the design an EV to remove the effect of scanner/center?
if I need to model that, Could be the following design correct?
GP EV1 EV2 EV3 EV4
1 1 0 1 0
1 1 0 1 0
1 1 0 1 0
2 0 1 0 1
2 0 1 0 1
2 0 1 0 1
EV1 for group 1(controls)
EV2 for group 2 (patients)
EV3 coming from center 1
EV4 coming from center 2
Contrats:
1. 1 -1 0 0 = control> patients
2. -1 1 0 0 = patients > controls
3. 1 0 0 0 = controls mean
4. 0 1 0 0 = patients mean
Thank you very much
Lorena Jimenez Castro, MD
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