Hi Saul
Sorry for delay - too much else on!
The reference is: Warfarin treatment in patients with atrial fibrillation:
Observing outcomes associated
with varying levels of INR control. Thrombosis Research 124 (2009) 37-41
It's not available on-line without a fee but I can send you a copy if
required
Robert
-----Original Message-----
From: GP-UK [mailto:[log in to unmask]] On Behalf Of Saul Galloway
Sent: 18 November 2011 16:41
To: [log in to unmask]
Subject: Re: Dabigatran (Pradaxa(R))
> a patient on warfarin with a TTR of <40% is at greater risk of a
thrombotic stroke than if they weren't on any anticoagulation at all.
This is counter-intuitive , could you point out a reference Robert?
On 15/11/2011, Robert Treharne Jones <[log in to unmask]> wrote:
> There are currently no antidotes available for either dabigatran or
> rivaroxaban, although you can be sure that the lab guys are burning
> the midnight oil trying to get something out of the door ASAP. The
> general feeling right now is that the half-life of these drugs is so
> short that it doesn't take as long as warfarin might to reduce to a
> level where surgery could be possible. For a patient who is on
> warfarin, of course, you can crash-reverse the anticoagulation process
> and have them on the theatre table inside half an hour - this is not
currently possible with dabigatran.
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> Robert
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> From: GP-UK [mailto:[log in to unmask]] On Behalf Of Jel Coward
>
> How to fix bleeding in the trauma patient in Emergency Dept?
>
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