Are there any all-D proteins out there, of known structure or
otherwise? If so, do enantiomer-specific catalyses become inverted?
JPK
On Wed, Feb 15, 2012 at 8:05 AM, David Schuller <[log in to unmask]> wrote:
> Wukovitz & Yeates (1995) Nature Struc. Biol. 2(12): 1062-1067
> predicts that the most probable space group for macromolecular
> crystallization is P -1 (P 1-bar). All you have to do to try it out is
> synthesize the all-D enantiomer of your protein and get it to fold properly.
>
>
> On 02/14/12 18:36, Prem Kaushal wrote:
>
>
> Hi
>
> We have a protein that crystallized in P21212 space group. We are looking
> for some different crystal forms. We tried few things did not work. Now we
> are thinking to mutate surface residues. Anybody aware of any software which
> can predict the mutations that might help in crystallizing protein in
> different space group, please inform me.
>
> Thanks in advance
>
> Prem
>
>
> --
>
>
>
> --
> =======================================================================
> All Things Serve the Beam
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> David J. Schuller
> modern man in a post-modern world
> MacCHESS, Cornell University
> [log in to unmask]
--
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Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
email: [log in to unmask]
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