A position is available in the Department of Biochemistry for a talented postdoctoral structural biologist to work on a new 3 year collaborative project with MRC Technology focussed on protein structure-based drug discovery and development. The scientist will work in the groups of Prof. Mark Carr and Dr Richard Bayliss, with a combination of NMR spectroscopy and X-ray crystallography used to determine the structures of proteins targeted by MRC Technology drug discovery programmes and to characterise their interactions with candidate drugs. The proposed work will involve close interactions with experienced research scientists at MRC Technology. The Department of Biochemistry is superbly equipped for all aspects of NMR spectroscopy and X-ray crystallography based structural biology, with excellent supporting facilities for recombinant protein expression and purification. The research fellow position will be supported by a dedicated, part-time (60%) protein biochemistry research assistant.
The successful postdoctoral research fellow will have a proven track record in either NMR spectroscopy or X-ray crystallography based structural biology, with some experience in NMR-based approaches desirable. A clear willingness and desire to apply either approach to solve protein structures is essential. A strong interest in knowledge-based drug discovery is also essential for the position. The ability and willingness to travel to meetings with collaborators and to use off-campus research facilities is essential. Good communication and presentation skills are also a pre-requisite.
Informal enquiries may be made to Prof. Mark Carr, Tel: +44 (0)116 229 7075, E.mail: [log in to unmask], or to Dr Richard Bayliss, Tel +44 (0)116 229 7100, E.mail [log in to unmask] Applications must be made through the University vacancies website, reference MBP00560.
http://www2.le.ac.uk/offices/personnel/job-vacancies/?newms=jj&id=73578&newlang=1
Closing date for applications is midnight on 11th March 2012
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Dr Richard Bayliss, Reader in Structural Biology
Department of Biochemistry
Henry Wellcome Building
University of Leicester
Lancaster Road, Leicester
LE2 9HN
Tel: 0116 2297100
Web: http://www2.le.ac.uk/departments/biochemistry/staff/richard-bayliss/
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