Position Description
Director of Biostatistics and Bioinformatics
Duke Cancer Institute

The Director of Biostatistics and Bioinformatics (DBB) is a senior faculty member of the Department of Biostatistics and Bioinformatics and a key member of the senior leadership of DCI, with responsibility for assuring appropriate statistical and bioinformatics infrastructure and staffing for DCI. The DBB is responsible for management of the statistical, data management, and information systems resources of the Duke Cancer Institute (DCI). The DBB works in partnership with the DCI Director and senior scientific leaders and administrative staff to achieve the overall goals of the DCI. The DBB also interacts as necessary with scientific, statistical, regulatory and administrative staff at the National Cancer Institute, the Food and Drug Administration, the pharmaceutical industry, and the cancer cooperative groups in the design, implementation and analysis of DCI studies.
For more information, contact Professor Gary Lyman at: [log in to unmask]

Position Summary and Activities

The DBB will be responsible for biostatistics and bioinformatics activities in the DCI, including faculty and staff within the DCI, and will ensure adequate and appropriate effort assignment.

As a member of the Executive Team of the Duke Cancer Institute (DCI) the DBB will participate in the strategic planning of scientific research in the DCI and will report to the Chair of the Biostatistics and Bioinformatics Department and to the Director of the DCI.

The DBB will participate in strategic discussions and decisions regarding aspects of DCI research that relate to biostatistics and bioinformatics, such as specimen banking, data management, and medical informatics.
The DBB will be responsible for the integration of biostatistics and bioinformatics activities with the other aspects of clinical and basic research at the DCI and, in particular, will work to ensure seamless integration of information technology functions with biostatistics and bioinformatics functions.

A priority of this role will be to plan for biostatistical support that is needed by each disease based group within the DCI and aid in its implementation throughout the DCI clinical research groups. Emphasis will focus on quality assurance efforts for biostatistics review in the development and implementation of protocols.
The DBB will provide statistically sound scientific guidance to peers, collaborators, and senior management, within both the DCI and the Department of Biostatistics and Bioinformatics.



The DBB will be responsible for assessing the biostatistics and bioinformatics needs and feasibility as decisions are made for the DCI to undertake major initiatives or expand into new areas. Areas include clinical research, genomics, population sciences and outcomes research.

The DBB will coordinate biostatistics and bioinformatics hiring needs within the DCI and will ensure that projects have adequate faculty statistical input, as well as staff statistical support.

The DBB will be responsible for ensuring continuity of biostatistics and bioinformatics effort on projects when original statistical faculty or staff are unavailable, for example during family leave, disability, or after resignations.

The DBB will serve as a liaison between the DCI leadership and the DCI biostatisticians and bioinformaticians. The DBB will be the Faculty leader for communications to ensure that faculty issues are represented.



The DBB will help designate a mentor for new B&B faculty members working in the DCI and will ensure appropriate training.


The DBB will serve as a liaison between the DCI and the Department of Biostatistics and Bioinformatics.

The DBB will collaborate on specific DCI research projects as required.


Minimum Requirements

This position will be filled by a member of the faculty in the Department of Biostatistics and Bioinformatics. A Ph.D. or equivalent degree in biostatistics, statistics, or bioinformatics is required. Prior cancer research experience and relevant management experience are also required. Excellent verbal and written communication skills and ability to collaborate effectively with non-statisticians are essential.
For more information, contact Professor Gary Lyman at: [log in to unmask]


Best wishes,
Emily Crowe, Ph.D.
Network Coordinator
MRC Network of Hubs for Trials Methodology Research
MRC Clinical Trials Unit

Aviation House

125 Kingsway

London

WC2B 6NH

Direct line: +44 (0)20 7670-4901

Main switchboard: +44 (0)20 7670-4700
Email: [log in to unmask]<mailto:[log in to unmask]>


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