How could they not be snapshots of conformations adopted in solution?
James
On Feb 10, 2012, at 1:25 PM, Jacob Keller wrote:
> Dear Crystallographers,
>
> I am looking for references which discuss the validity of the
> assertion that multiple crystal structures of the same or similar
> proteins can be considered freeze-frame snapshots of actual
> conformations assumed in solution. In a way, the assertion seems
> almost definitely true to me, but on the other hand, I could imagine
> some objections as well. Seems there should be some classic literature
> here...
>
> All the best,
>
> Jacob
>
>
>
> --
> *******************************************
> Jacob Pearson Keller
> Northwestern University
> Medical Scientist Training Program
> email: [log in to unmask]
> *******************************************
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