(Old thread, just cleaning up, sorry...)
I thought James' algorithm didn't do anything to the spots, just to the
stuff in between.
So one obvious way to handle this is for the data processing programs to
be looking between the integrated spots as well, whether they're missing
anything; they could then flag it up if they are, prompting the
experimenter to haul out the originals.
I mean, data processing programs are looking between spots already,
aren't th... oh. Right. Sorry, silly me. Well, maybe they should.
Considering that's the reason we're pushing terabytes around cyberspace,
according to this thread. Personally I'd already be happy with an
indication of how many spots I'm not integrating.
phx.
On 08/11/2011 12:17, Herbert J. Bernstein wrote:
> Um, but isn't Crystallograpy based on a series of
> one-way computational processes:
> photons -> images
> images -> {struture factors, symmetry}
> {structure factors, symmetry, chemistry} -> solution
> {structure factors, symmetry, chemistry, solution}
> -> refined solution
>
> At each stage we tolerate a certain amount of noise
> in "going backwards". Certainly it is desirable to
> have the "original data" to be able to go forwards,
> but until the arrival of pixel array detectors, we
> were very far from having the true original data,
> and even pixel array detectors don't capture every
> single photon.
>
> I am not recommending lossy compressed images as
> a perfect replacement for lossless compressed images,
> any more than I would recommend structure factors
> are a replacement for images. It would be nice
> if we all had large budgets, huge storage capacity
> and high network speeds and if somebody would repeal
> the speed of light and other physical constraints, so that
> engineering compromises were never necessary, but as
> James has noted, accepting such engineering compromises
> has been of great value to our colleagues who work
> with the massive image streams of the entertainment
> industry. Without lossy compression, we would not
> have the _higher_ image quality we now enjoy in the
> less-than-perfectly-faithful HDTV world that has replaced
> the highly faithful, but lower capacity, NTSC/PAL world.
>
> Please, in this, let us not allow the perfect to be
> the enemy of the good. James is proposing something
> good.
>
> Regards,
> Herbert
> =====================================================
> Herbert J. Bernstein
> Professor of Mathematics and Computer Science
> Dowling College, Kramer Science Center, KSC 121
> Idle Hour Blvd, Oakdale, NY, 11769
>
> +1-631-244-3035
> [log in to unmask]
> =====================================================
>
> On Tue, 8 Nov 2011, Harry Powell wrote:
>
>> Hi
>>
>>> I am not a fan
>>> of one-way computational processes with unique data.
>>>
>>> Thoughts anyone?
>>>
>>> Cheerio,
>>>
>>> Graeme
>> I agree.
>>
>> Harry
>> --
>> Dr Harry Powell, MRC Laboratory of Molecular Biology, MRC Centre, Hills Road, Cambridge, CB2 0QH
>>
>> http://www.iucr.org/resources/commissions/crystallographic-computing/schools/mieres2011
>>
|