Dear SPMers,
we have investigated the face-processing network in two lesion patients using a face-perception fMRI task (block-design). To examine differences between patients we have compared each patient with the same group of matched controls (using Rik Hensons `comparing a single patient versus a group of controls`approach).
Now the reviewers ask for a direct contrast between the two patients. My question: is it possible to directly compare two subjects using spm? Would a comparison on the first level between the patients lead to valid results?
Thanks in advance & best regards,
Ben
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