Try the program DIBER to evaluate the likelihood your crystal contained ordered nucleic acid in addition to protein. See Acta Cryst. (2010). D66, 643-653 “DIBER: protein, DNA, or both?” by G. Chojnowski & M. Bochtler.
Good luck, Pete
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From: CCP4 bulletin board [[log in to unmask]] On Behalf Of zq deng [[log in to unmask]]
Sent: Friday, September 30, 2011 8:36 PM
To: [log in to unmask]
Subject: [ccp4bb] detect dsDNA
Hi all,
.
recently,I got a crystal of protein-DNA crystal.i used silver stainto prove that it is a protein crystal.Does anyone have method to detect if there is DNA in the crystal.
any suggestion will be appreciated.
Regards,
deng
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