Dear FSL community,
I asked a question related to this a few weeks ago, but now have a more basic question.
I am looking at a FA and RD differences between a clinical group and controls. We have acquired various neurocognitive and neuropsychological measures on these groups.
One set of scores that I am interested in are RBANS scores; a neurospsych test that includes various domains, e.g., immediate memory, delayed memory, visuospatial constructional skills, etc.
Most of the scores show significant differences between the groups, except for visuospatial scores. In regards to FA and RD alone, I see no differences between the groups.
My question is what does it mean to add these as EVs/confounds/whatever you want to call them in a randomise analysis? In other words, if I were to find some significant results indicating FA differences in regards to immediate memory, what additional information am I gathering from this that could be useful clinically? Similarly, what if I found significant results in regards to visuospatial scores, which didn't show any differences previously?
I know that at a basic level the randomise results are indicating there is a difference in the slope of the scores. I just would like an explanation of the bigger picture.
Many thanks,
Carlos
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