Dear David,
I'm afraid that there is no automatic, robust and reliable way of doing this with
publicly available tools at present (as far as I know). You could try looking at
the ratio of the PD and T1 image, as this can often highlight changes, but I
think you'll have to go with a manual or semi-automatic method of delineating
the hyperintensities (for example, a combination of thresholding, tissue
segmentation, and manual editing might work).
All the best,
Mark
On 21 Sep 2011, at 20:04, David Lahna wrote:
> Can anyone suggest a tool or workflow pipeline I could use to automatically segment white matter hyperintensities?
>
> I have T1, T2 and proton density scans to work with but FLAIR images are unfortunately not available.
>
> Any ideas are appreciated. Thanks in advance.
>
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