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ACB-CLIN-CHEM-GEN  September 2011

ACB-CLIN-CHEM-GEN September 2011

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Subject:

Re: Blood ketone testing

From:

Rita Horvath <[log in to unmask]>

Reply-To:

Rita Horvath <[log in to unmask]>

Date:

Tue, 6 Sep 2011 08:52:49 +1000

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (185 lines)

This view is very much supported by the ketones chapter of the recently issued NACB guideline and what the references cited in its evidence table refer to.
The guideline can be downloaded from NACB's home page (http://www.aacc.org/members/nacb/LMPG/Pages/default.aspx)


Regards, Rita
Prof. Andrea Rita Horvath 
Clinical Director 
SEALS North, Department of Clinical Chemistry 
Level 4, Campus Centre, Prince of Wales Hospital 
Barker Street, Randwick, NSW 2031, Sydney, Australia 
Tel: (+612)-9382 9078 
Fax: (+612)-9382 9099 
Mobile No: (+61)-404 027 843. 



-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of OKane, Maurice
Sent: Monday, 5 September 2011 11:21 PM
To: [log in to unmask]
Subject: Re: Blood ketone testing

This e-mail is covered by the disclaimer found at the end of the message.

Wayne

 

Although there have been a few small studies, there is no robust evidence that home ketone testing has any impact on DKA rates. I think this would actually be very difficult to show, as DKA has a relatively infrequent event rate  per patient per year and would therefore require large, longish term studies. More importantly,  any sort of home testing like this as part of a self management package represents  a complex intervention and it is very difficult to eliminate confounding e.g. patients who perform appropriate ketone self monitoring are likely to be good at other aspects of self management also etc etc. 

 

We provide POCT ketone testing to limited clinical areas within the hospital. There is some evidence for the role of ketone measurement  in the treatment of DKA.

 

Best wishes

 

Maurice

 

Dr Maurice O'Kane

Consultant Chemical Pathologist

Altnagelvin hospital

Western Health and Social Care Trust

Londonderry

N.  Ireland

 

From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Bradbury Wayne (RNL) North Cumbria University Hospitals
Sent: 05 September 2011 12:36
To: [log in to unmask]
Subject: Blood ketone testing

 

Hello all,

 

We are in the process of rolling out PoCT meters to test for beta-hydroxy butyrate on a 

limited number of wards for patients with DKA. This will help our Trust comply with the 

guideline published last year by the Joint British Diabetes Societies. See this link.....

 

http://www.diabetes.nhs.uk/document.php?o=1336

 

Our pharmacy dept. are concerned about the costs of this development, as they pay 

for the test strips which are approximately £2 each. 

 

An associated issue is the practice of meter companies supplying free meters to patients 

for use at home on the basis that this will reduce DKA admissions. Is this true?

 

I guess most of you already provide, or are planning to introduce PoCT but have any of you 

decided not to go down this route and only provide testing from the lab on either your main 

analytical platform or by using a meter?  

 

Alternatively have any of you looked at this issue and decided not to provide blood ketone 

testing at all?

 

Please reply to the list or, if you want anonymity and I receive more than a couple of replies

I'll collate them and post back to the list by the end of the week.

 

Thanks,

 

Wayne.

 

Mr WH Bradbury

Consultant Biochemist

Biochemistry Department

Cumberland Infirmary

CARLISLE

Cumbria 

CA2 7HY

Tel:     01228 814521

Fax:    01228 814831

E-mail: [log in to unmask] <mailto:[log in to unmask]>    

 

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