Hi Folks,
I'm analyzing 2 groups (n=20 for each group) using the 2-group t-test option and finding no differences between the groups at FWE 0.05/FWE 0.10, and very minimal differences at p=0.001 uncorrected.
I've looked at each subjects' data to make sure the pre-processed scans are okay, and that the group contrasts are correct. The activation patterns for each group separately (1 group t test) show activation in the hypothesized regions. Visually, the two groups have similar activation patterns, but are by no means "the same", as the clinical group shows clusters of activation at the single group level (FWE 0.05) that are not shown in the control group. Obviously the differences have to be robust/reliable enough to survive the statistical contrast, but I was wondering if there is anything else I can do to elucidate differences between these groups? All suggestions welcome.
Thanks,
Doug
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