Hi Neil,
yes, you get into all kinds of trouble when working with children ;) But
seriously, first: is this normalized data? Otherwise the correspondance
with the glass brain is not necessarily meaningful, and overlaying the
activation on the individual T1 will help you more.
If the data is normalized, it looks like something has gone wrong with
masking out non-brain areas, or normalization, or both, the question is,
why. You should check the mask.img in the results directory, and check
the EPI images in a movie loop - if there was really a lot of motion,
realignment will not be able to compensate for it. If you stil the the
brain jump around following realignment, you will have to consider
throwing the data away.
I am not sure where art_repair comes into play here, but the
"activation" in/next to the cerebellum is present in both analyses, only
more pronounced in the one versus the other (and hey, .001 is not very
stringent, so some schmutz is to be expected). This is just what I can
think of right now. Let us know what transpired when you found out.
Cheers,
Marko
NILANJAN KAYAL wrote:
> Dear All,
>
> I have been using spm8 for quite sometime now but have never encountered
> a problem like this before. A colleague of mine works with children as a
> part of her study and recently she came to me with a set of results
> after analyzing it with spm8. I have attached the image files with this
> email, please have a look. The image file named as block2 is obtained
> after analyzing it with spm8 and there were no toolbox extensions used.
> However the image file named as scan1 has been analyzed using ArtRepair
> before doing the first level analysis. The threshold used in both the
> cases were 0.001. Somehow the clusters formed are outside the area of
> the brain. I wonder what are the probable causes for this to happen? I
> have also attached a study outline file for giving you the idea about
> the design matrix.
>
> I would really appreciate your help.
>
> Cheers,
> Neil
>
> --
> ------------------------------------------
> Nilanjan Kayal
> Graduate Research Assistant
> MR Lab, Dept of Radiology
> Temple University Hospital
> Office: (215) 707-9439 <tel:%28215%29%20707-9439>
> Mobile:(304) 594-6880 <tel:%28304%29%20594-6880>
>
>
--
____________________________________________________
PD Dr. med. Marko Wilke
Facharzt für Kinder- und Jugendmedizin
Leiter, Experimentelle Pädiatrische Neurobildgebung
Universitäts-Kinderklinik
Abt. III (Neuropädiatrie)
Marko Wilke, MD, PhD
Pediatrician
Head, Experimental Pediatric Neuroimaging
University Children's Hospital
Dept. III (Pediatric Neurology)
Hoppe-Seyler-Str. 1
D - 72076 Tübingen, Germany
Tel. +49 7071 29-83416
Fax +49 7071 29-5473
[log in to unmask]
http://www.medizin.uni-tuebingen.de/kinder/epn
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