Dear Dr. Gitelman and others
We have an event related design and are interested in the main effect of the
task, the main effect of 'basal connectivity' (i.e. connectivity throughout
the task, not just at event times) with a seed region, and the interaction.
We are comparing two groups of participants and hypothesise differences for
the main effects and interaction.
When we do this analysis we do find interesting significant differences.
However is it valid to use the main effect of the BOLD signal from the seed
region as above? Publications I have found tend only to report the
interaction.
Many thanks for your advice
Douglas
|